Medical and genomics data standardization, analysis and decision support

Author: Piotr Lukasiak

Abstract:

A comprehensive set of reference databases has been developed for all biological and bioinformatics projects conducted in the field of genetic and genomic analysis. A distinctive IT platform facilitates the utilization of artificial intelligence for pioneering research that integrates multidimensional biomedical and clinical data. Implemented bioinformatics tools and heterogeneous data standardization systems provide the means for the analysis of genetic determinants of diverse disease entities.

Related founding:

• ECBiG – European Centre for Bioinformatics and Genomics – MOSAIC (MultiOmicS and Artificial Intelligence for Clinical practice), the Smart Growth Operational Programme 2014-2020, POIR.04.02.00-00-D017/20, (2021 – 2023), Polish Roadmap for Research Infrastructure
• ECBiG – European Centre for Bioinformatics and Genomics – GMP (Genomic Map of Poland), the Smart Growth Operational Programme 2014-2020, POIR.04.02.00-30-A004/16, (2016 – 2023), Polish Roadmap for Research Infrastructure
• CompuVac (Grant agreement ID: 5246), (2005 – 2010), Rational design and standardized evaluation of novel genetic vaccines, 6th Framework Program of European Commission

Related publications:

• Witczak, D., Sychla, K., Wysocka, J., Laskowski, A., Frohmberg, W., Lukasiak, P., Blazewicz, J., Swiercz, A., GrassSV – hybrid method to detect structural variants in high throughput DNA-seq data, Bioinformatics (under review), 2024
• Wojciechowski, P., Krause, K., Lukasiak, P., Blazewicz, J., The correctness of large scale analysis of genomic data. Foundations of Computing and Decision Sciences. 2021, 46 (4), 423-436
• Lukasiak, P., Antczak, M., Ratajczak, T., Szachniuk, M., Popenda, M., Adamiak, R.W., Blazewicz, J., RNAssess –  a  web   server  for quality assessment  of  RNA  3D  structures.  Nucleic Acids Research, 2015, 43(W1), pp. W502-506
• Blazewicz, J., Borowski, M., Chaara, W., Kedziora, P., Klatzmann, D., Lukasiak P., Six, A., Wojciechowski, P., GeVaDSs–decision support system for novel Genetic Vaccine development process. BMC Bioinformatics, 2012, 13, 1-16
• Blazewicz, J., Lukasiak, P., System wspomagania wytwarzania i analizy szczepionek genetycznych. Kosmos, 2009, 58 (1-2), 113-126

Related patents:

• European Center for Bioinformatics and Genomics, Protection right no: R.363593 – joint protection right with Poznań University of Technology (ECBiG), Application no: Z.538606, Date of granting: 11.05.2023